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Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo

Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of several pathologies; thus, elucidating the pathways by which they induce cellular transformation is critical. Althou...

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Detalles Bibliográficos
Autores principales:	Chang, Shiou-chi, Fedeles, Bogdan I., Wu, Jie, Delaney, James C., Li, Deyu, Zhao, Linlin, Christov, Plamen P., Yau, Emily, Singh, Vipender, Jost, Marco, Drennan, Catherine L., Marnett, Lawrence J., Rizzo, Carmelo J., Levine, Stuart S., Guengerich, F. Peter, Essigmann, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477646/ https://www.ncbi.nlm.nih.gov/pubmed/25837992 http://dx.doi.org/10.1093/nar/gkv243

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