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The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA–DNA hybrids

Telomerase is an enzyme that adds repetitive DNA sequences to the ends of chromosomes and consists of two main subunits: the telomerase reverse transcriptase (TERT) protein and an associated telomerase RNA (TER). The telomerase essential N-terminal (TEN) domain is a conserved region of TERT proposed...

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Detalles Bibliográficos
Autores principales:	Akiyama, Benjamin M., Parks, Joseph W., Stone, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477650/ https://www.ncbi.nlm.nih.gov/pubmed/25940626 http://dx.doi.org/10.1093/nar/gkv406

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