Signatures of accelerated somatic evolution in gene promoters in multiple cancer types

Cancer-associated somatic mutations outside protein-coding regions remain largely unexplored. Analyses of the TERT locus have indicated that non-coding regulatory mutations can be more frequent than previously suspected and play important roles in oncogenesis. Using a computational method called SAS...

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Detalles Bibliográficos
Autores principales: Smith, Kyle S., Yadav, Vinod K., Pedersen, Brent S., Shaknovich, Rita, Geraci, Mark W., Pollard, Katherine S., De, Subhajyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477653/
https://www.ncbi.nlm.nih.gov/pubmed/25934800
http://dx.doi.org/10.1093/nar/gkv419

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