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Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation

Polypyrimidine tract binding protein (PTBP1) is a widely expressed RNA binding protein that acts as a regulator of alternative splicing and of cytoplasmic mRNA functions. Vertebrates contain two closely-related paralogs with >75% amino acid sequence identity. Early replacement of PTBP1 by PTBP2 d...

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Detalles Bibliográficos
Autores principales:	Tan, Lit-Yeen, Whitfield, Peter, Llorian, Miriam, Monzon-Casanova, Elisa, Diaz-Munoz, Manuel D., Turner, Martin, Smith, Christopher W.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477659/ https://www.ncbi.nlm.nih.gov/pubmed/25940628 http://dx.doi.org/10.1093/nar/gkv429

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