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Mitochondrial translocation of APE1 relies on the MIA pathway

APE1 is a multifunctional protein with a fundamental role in repairing nuclear and mitochondrial DNA lesions caused by oxidative and alkylating agents. Unfortunately, comprehensions of the mechanisms regulating APE1 intracellular trafficking are still fragmentary and contrasting. Recent data demonst...

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Detalles Bibliográficos
Autores principales:	Barchiesi, Arianna, Wasilewski, Michal, Chacinska, Agnieszka, Tell, Gianluca, Vascotto, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477663/ https://www.ncbi.nlm.nih.gov/pubmed/25956655 http://dx.doi.org/10.1093/nar/gkv433

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