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Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis

During the early steps of ribosome biogenesis in mammals, the two ribosomal subunits 40S and 60S are produced via splitting of the large 90S pre-ribosomal particle (90S) into pre-40S and pre-60S pre-ribosomal particles (pre-40S and pre-60S). We previously proposed that replacement of fibrillarin by...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Harunori, Ishikawa, Hideaki, Izumikawa, Keiichi, Miura, Yutaka, Hayano, Toshiya, Isobe, Toshiaki, Simpson, Richard J., Takahashi, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477673/
https://www.ncbi.nlm.nih.gov/pubmed/25969445
http://dx.doi.org/10.1093/nar/gkv470