Cargando…

MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2

MiRNAs play important roles in tumorigenesis. This study focused on exploring the effects and regulation mechanism of miRNA-137 on the biological behaviors of gastric cancer. Total RNA was extracted from tissues of 100 patients with gastric cancer and from four gastric cancer cell lines. Expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Liping, Chen, Jingtao, Ding, Chunsheng, Wei, Shutang, Zhu, Yanhong, Yang, Wenyi, Zhang, Xiaoyang, Wei, Xuejv, Han, Dazheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477888/ https://www.ncbi.nlm.nih.gov/pubmed/26102366 http://dx.doi.org/10.1371/journal.pone.0130124

Ejemplares similares

Retraction: MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2
Publicado: (2023)

LncRNA HULC shRNA disinhibits miR-377-5p to suppress the growth and invasion of hepatocellular carcinoma in vitro and hepatocarcinogenesis in vivo
por: Yan, Chunxiao, et al.
Publicado: (2020)

Dampening Enthusiasm for Circulating MicroRNA in Breast Cancer
por: Leidner, Rom S., et al.
Publicado: (2013)

MicroRNA-373 is upregulated and targets TNFAIP1 in human gastric cancer, contributing to tumorigenesis
por: ZHANG, XIAOTING, et al.
Publicado: (2013)

TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137
por: Wang, Sheng, et al.
Publicado: (2020)

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia
por: Goekeri, Cengiz, et al.
Publicado: (2023)

Analysis of the complementarity determining regions β-chain genomic rearrangement using high-throughput sequencing in periphery cytotoxic T lymphocytes of patients with chronic hepatitis B
por: HUANG, YINUO, et al.
Publicado: (2016)

Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia
por: Wright, C, et al.
Publicado: (2016)

MicroRNA-1305 Inhibits the Stemness of LCSCs and Tumorigenesis by Repressing the UBE2T-Dependent Akt-Signaling Pathway
por: Wei, Xiaoyong, et al.
Publicado: (2019)

Dampening of expression oscillations by synchronous regulation of a microRNA and its target
por: Kim, Dong hyun, et al.
Publicado: (2013)

Contributions of Costimulatory Molecule CD137 in Endothelial Cells
por: Yuan, Wei, et al.
Publicado: (2021)

Suppression of ANT2 by miR-137 Inhibits Prostate Tumorigenesis
por: Zhang, Heyuan, et al.
Publicado: (2021)

microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of XIAP
por: Li, Xiaodi, et al.
Publicado: (2017)

FoxD3-regulated microRNA-137 suppresses tumour growth and metastasis in human hepatocellular carcinoma by targeting AKT2
por: Liu, Li-Li, et al.
Publicado: (2014)

Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2
por: Mi, Ting-Wei, et al.
Publicado: (2020)

MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer
por: Shen, Hua, et al.
Publicado: (2016)

To dampen demyelination
por: Maxmen, Amy
Publicado: (2010)

Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models
por: Blanco-Aparicio, Carmen, et al.
Publicado: (2010)

Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression
por: Smith, Amber R., et al.
Publicado: (2015)

Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese
por: Lu, Weihong, et al.
Publicado: (2017)

The Differential DNA Hypermethylation Patterns of microRNA-137 and microRNA-342 Locus in Early Colorectal Lesions and Tumours
por: Kashani, Elham, et al.
Publicado: (2019)

MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability
por: Liu, L, et al.
Publicado: (2017)

Circulating microRNA miR-137 as a stable biomarker for methamphetamine abstinence
por: Kim, Baeksun, et al.
Publicado: (2022)

miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling
por: Zhang, Lihui, et al.
Publicado: (2021)

Schizophrenia plausible protective effect of microRNA-137 is potentially related to estrogen and prolactin in female patients
por: Peng, Qian, et al.
Publicado: (2023)

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway
por: Liu, Jia, et al.
Publicado: (2014)

The Role of microRNAs in the Tumorigenesis of Ovarian Cancer
por: Di Leva, Gianpiero, et al.
Publicado: (2013)

microRNA-1301-mediated inhibition of tumorigenesis
por: FANG, LIN, et al.
Publicado: (2011)

MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling
por: Chu, Shao-Jun, et al.
Publicado: (2016)

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation
por: Zhou, Wenqing, et al.
Publicado: (2018)

MicroRNA-137 Targets Carboxyl-terminal Binding Protein 1 in Melanoma Cell Lines
por: Deng, Yu, et al.
Publicado: (2011)

MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12
por: He, Zhiwei, et al.
Publicado: (2019)

Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism
por: Dong, J, et al.
Publicado: (2017)

Identification of microRNAs Involved in Regeneration of the Secondary Vascular System in Populus tomentosa Carr
por: Tang, Fang, et al.
Publicado: (2016)

Cortactin contributes to the tumorigenesis of gastric cancer by activating ERK/MMP pathway
por: Zhao, Yi, et al.
Publicado: (2023)

MicroRNA-431-5p Inhibits the Tumorigenesis of Osteosarcoma Through Targeting PANX3
por: Sun, Shengliang, et al.
Publicado: (2020)

MicroRNA-137 Inhibited Hypoxia-Induced Proliferation of Pulmonary Artery Smooth Muscle Cells by Targeting Calpain-2
por: Ge, Xiao-Yue, et al.
Publicado: (2021)

Ubiquitin signaling in cell cycle control and tumorigenesis
por: Dang, Fabin, et al.
Publicado: (2020)

The ESRP1-GPR137 axis contributes to intestinal pathogenesis
por: Mager, Lukas Franz, et al.
Publicado: (2017)

A Concise Review of MicroRNA-383: Exploring the Insights of Its Function in Tumorigenesis
por: Yi, Qian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f41vrc097co6tlp70dj81ji6c6