Cargando…

Synthesis of Heteroaryl Sulfonamides from Organozinc Reagents and 2,4,6-Trichlorophenyl Chlorosulfate

[Image: see text] A method for the preparation of aryl and heteroaryl sulfonamides using 2,4,6-trichlorophenyl chlorosulfate (TCPC) is described. The reaction of 2-pyridylzinc reagents with TCPC resulted in 2,4,6-trichlorophenyl (TCP) pyridine-2-sulfonates, and the parent pyridine-2-sulfonate was sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colombe, James R., DeBergh, J. Robb, Buchwald, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477900/ https://www.ncbi.nlm.nih.gov/pubmed/26065317 http://dx.doi.org/10.1021/acs.orglett.5b01540

Ejemplares similares

N-(2,4,6-Trichlorophenyl)maleamic acid
por: Shakuntala, K., et al.
Publicado: (2011)

(E)-Benzaldehyde (2,4,6-trichlorophenyl)hydrazone
por: Huang, Yan-Lan, et al.
Publicado: (2011)

Mechanistic Studies of the TRIP-Catalyzed Allylation with Organozinc Reagents
por: Hartmann, Peter E., et al.
Publicado: (2020)

2-[(E)-(2,4,6-Trichlorophenyl)iminomethyl]phenol
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides
por: Yang, Yang, et al.
Publicado: (2014)

Coupling of α,α-difluoro-substituted organozinc reagents with 1-bromoalkynes
por: Zemtsov, Artem A, et al.
Publicado: (2015)

Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts
por: Horan, Alexandra M., et al.
Publicado: (2021)

1-(4-Chlorobenzoyl)-3-(2,4,6-trichlorophenyl)thiourea hemihydrate
por: Khawar Rauf, M., et al.
Publicado: (2008)

Dimethyl 2-[2-(2,4,6-trichlorophenyl)hydrazin-1-ylidene]butanedioate
por: Usha, M. K., et al.
Publicado: (2013)

Generation of Organozinc Reagents by Nickel Diazadiene Complex Catalyzed Zinc Insertion into Aryl Sulfonates
por: Klein, Philippe, et al.
Publicado: (2019)

Copper(I)-Catalyzed Cross-Coupling of 1-Bromoalkynes with N-Heterocyclic Organozinc Reagents
por: Frabitore, Christian, et al.
Publicado: (2022)

2,2′-[1-(2,4,6-Trichlorophenyl)-1H-1,2,4-triazole-3,5-diyl]diphenol
por: Li, Zhong-Shu, et al.
Publicado: (2008)

Dosage Delivery of Sensitive Reagents Enables Glove Box-Free Synthesis
por: Sather, Aaron C., et al.
Publicado: (2015)

Transition‐Metal‐Free Synthesis of Polyfunctional Triarylmethanes and 1,1‐Diarylalkanes by Sequential Cross‐Coupling of Benzal Diacetates with Organozinc Reagents
por: Wei, Baosheng, et al.
Publicado: (2021)

Synthesis of Trimeric Organozinc Compounds and their Subsequent Reaction with Oxygen
por: Manzi, Joe A., et al.
Publicado: (2016)

A practical route to tertiary diarylmethylamides or -carbamates from imines, organozinc reagents and acyl chlorides or chloroformates
por: Le Gall, Erwan, et al.
Publicado: (2011)

4-(4-Fluorophenyl)-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-1H-pyrazol-5-amine
por: Abu Thaher, Bassam, et al.
Publicado: (2012)

Layered zinc hydroxide monolayers by hydrolysis of organozincs
por: Leung, Alice H. M., et al.
Publicado: (2018)

Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
por: Cheng, Xinyi, et al.
Publicado: (2021)

Nickel-catalyzed acylzincation of allenes with organozincs and CO
por: Wu, Xianqing, et al.
Publicado: (2023)

Synthesis, crystal structure, Hirshfeld surface analysis, DFT, molecular docking and molecular dynamic simulation studies of (E)-2,6-bis(4-chlorophenyl)-3-methyl-4-(2-(2,4,6-trichlorophenyl)hydrazono)piperidine derivatives
por: Anthony, L. Athishu, et al.
Publicado: (2022)

Catalyst-Free Formal Conjugate Addition/Aldol or Mannich Multicomponent Reactions of Mixed Aliphatic Organozinc Reagents, π-Electrophiles and Michael Acceptors
por: Pinaud, Marine, et al.
Publicado: (2023)

In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides
por: Milner, Phillip J., et al.
Publicado: (2015)

Ethyl 5-amino-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-1H-pyrazole-4-carboxylate dimethyl sulfoxide hemisolvate
por: Abu Thaher, Bassam, et al.
Publicado: (2012)

Organozinc Precursor-Derived Crystalline ZnO Nanoparticles: Synthesis, Characterization and Their Spectroscopic Properties
por: Liang, Yucang, et al.
Publicado: (2018)

Palladium-Catalyzed Hydroxylation of Aryl and Heteroaryl Halides Enabled by the Use of a Palladacycle Precatalyst
por: Cheung, Chi Wai, et al.
Publicado: (2014)

N-(2,4,5-Trichlorophenyl)maleamic acid
por: Gowda, B. Thimme, et al.
Publicado: (2009)

Recent Advance in Heterocyclic Organozinc and Organomanganese Compounds; Direct Synthetic Routes and Application in Organic Synthesis
por: Kim, Seung-Hoi, et al.
Publicado: (2010)

Palladium-catalysed synthesis of triaryl(heteroaryl)methanes
por: Zhang, Shuguang, et al.
Publicado: (2017)

Iron‐Mediated Electrophilic Amination of Organozinc Halides using Organic Azides
por: Graßl, Simon, et al.
Publicado: (2019)

1-Benzoyl-3-(2,4,5-trichlorophenyl)thiourea
por: Rauf, M. Khawar, et al.
Publicado: (2011)

2,2-Diphenyl-N-(2,4,5-trichlorophenyl)acetamide
por: Fun, Hoong-Kun, et al.
Publicado: (2012)

Poly[μ-aqua-μ(5)-[2-(2,3,6-trichlorophenyl)acetato]-caesium]
por: Smith, Graham
Publicado: (2013)

One-Pot Synthesis and Applications of N-Heteroaryl Iodonium Salts
por: Bielawski, Marcin, et al.
Publicado: (2014)

A practical and scalable system for heteroaryl amino acid synthesis
por: Aycock, R. A., et al.
Publicado: (2017)

Synthesis and evaluation of new heteroaryl nitrones with spin trap properties
por: Barriga-González, G., et al.
Publicado: (2020)

Synthesis, in vitro bioassays, and computational study of heteroaryl nitazoxanide analogs
por: Ahmed, Tasmia, et al.
Publicado: (2021)

Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N-Sulfinyl-O-(tert-butyl)hydroxylamine, t-BuONSO
por: Davies, Thomas Q., et al.
Publicado: (2020)

Sydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis
por: Albota, Florin, et al.
Publicado: (2016)

Crystal structure of N-[(1S,2S)-2-aminocyclohexyl]-2,4,6-trimethylbenzenesulfonamide
por: Ngassa, Felix N., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_aniveocg3s25125adcvbvbv7lo