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Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies

Alpha-2-macroglobulin is an abundant secreted protein that is of particular interest because of its diverse ligand binding profile and multifunctional nature, which includes roles as a protease inhibitor and as a molecular chaperone. The activities of alpha-2-macroglobulin are typically dependent on...

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Detalles Bibliográficos
Autores principales: Wyatt, Amy R., Kumita, Janet R., Farrawell, Natalie E., Dobson, Christopher M., Wilson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477937/
https://www.ncbi.nlm.nih.gov/pubmed/26103636
http://dx.doi.org/10.1371/journal.pone.0130036