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Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies
Alpha-2-macroglobulin is an abundant secreted protein that is of particular interest because of its diverse ligand binding profile and multifunctional nature, which includes roles as a protease inhibitor and as a molecular chaperone. The activities of alpha-2-macroglobulin are typically dependent on...
Autores principales: | Wyatt, Amy R., Kumita, Janet R., Farrawell, Natalie E., Dobson, Christopher M., Wilson, Mark R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477937/ https://www.ncbi.nlm.nih.gov/pubmed/26103636 http://dx.doi.org/10.1371/journal.pone.0130036 |
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