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LPS Down-Regulates Specificity Protein 1 Activity by Activating NF-κB Pathway in Endotoxemic Mice

BACKGROUND: Specificity protein (Sp) 1 mediates the transcription of a large number of constitutive genes encoding physiological mediators. NF-κB mediates the expression of hundreds of inducible genes encoding pathological mediators. Crosstalk between Sp1 and NF-κB pathways could be pathophysiologic...

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Detalles Bibliográficos
Autores principales:	Ye, Xiaobing, Liu, Hong, Gong, Yong-Sheng, Liu, Shu Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478004/ https://www.ncbi.nlm.nih.gov/pubmed/26103469 http://dx.doi.org/10.1371/journal.pone.0130317

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