Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease

BACKGROUND: PET radiopharmaceuticals capable of imaging β-amyloid (Aβ) plaque burden in the brain could offer highly valuable diagnostic tools for clinical studies of Alzheimer’s disease. To further supplement existing armamentarium of FDA-approved agents as well as those under development, and to c...

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Detalles Bibliográficos
Autores principales: Sundaram, Guruswami SM, Dhavale, Dhruva, Prior, Julie L, Sivapackiam, Jothilingam, Laforest, Richard, Kotzbauer, Paul, Sharma, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478171/
https://www.ncbi.nlm.nih.gov/pubmed/26061601
http://dx.doi.org/10.1186/s13550-015-0112-4

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