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Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases
Wells’ syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here, we r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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S. Karger AG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478307/ https://www.ncbi.nlm.nih.gov/pubmed/26120307 http://dx.doi.org/10.1159/000432392 |
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author | Cormerais, Maxence Poizeau, Florence Darrieux, Laure Tisseau, Laurent Safa, Gilles |
author_facet | Cormerais, Maxence Poizeau, Florence Darrieux, Laure Tisseau, Laurent Safa, Gilles |
author_sort | Cormerais, Maxence |
collection | PubMed |
description | Wells’ syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here, we report two cases of WS that masqueraded as bacterial facial cellulitis. Under treatment with oral prednisone and/or a combination therapy with levocetirizine and hydroxyzine, both patients showed a dramatic improvement of the skin lesions. These cases highlight the need for clinicians to consider WS in the differential diagnosis when evaluating a patient with facial cellulitis that does not respond to an initial antimicrobial regimen. In addition, our cases suggest that combination therapy with levocetirizine and hydroxyzine may be successfully used as corticosteroid-sparing treatment or to prevent relapse after the discontinuation of corticosteroid treatment. |
format | Online Article Text |
id | pubmed-4478307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-44783072015-06-26 Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases Cormerais, Maxence Poizeau, Florence Darrieux, Laure Tisseau, Laurent Safa, Gilles Case Rep Dermatol Published online: June, 2015 Wells’ syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here, we report two cases of WS that masqueraded as bacterial facial cellulitis. Under treatment with oral prednisone and/or a combination therapy with levocetirizine and hydroxyzine, both patients showed a dramatic improvement of the skin lesions. These cases highlight the need for clinicians to consider WS in the differential diagnosis when evaluating a patient with facial cellulitis that does not respond to an initial antimicrobial regimen. In addition, our cases suggest that combination therapy with levocetirizine and hydroxyzine may be successfully used as corticosteroid-sparing treatment or to prevent relapse after the discontinuation of corticosteroid treatment. S. Karger AG 2015-06-09 /pmc/articles/PMC4478307/ /pubmed/26120307 http://dx.doi.org/10.1159/000432392 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only. |
spellingShingle | Published online: June, 2015 Cormerais, Maxence Poizeau, Florence Darrieux, Laure Tisseau, Laurent Safa, Gilles Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title | Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title_full | Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title_fullStr | Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title_full_unstemmed | Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title_short | Wells’ Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
title_sort | wells’ syndrome mimicking facial cellulitis: a report of two cases |
topic | Published online: June, 2015 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478307/ https://www.ncbi.nlm.nih.gov/pubmed/26120307 http://dx.doi.org/10.1159/000432392 |
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