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Conserved RNA secondary structures and long-range interactions in hepatitis C viruses

Hepatitis C virus (HCV) is a hepatotropic virus with a plus-strand RNA genome of ∼9.600 nt. Due to error-prone replication by its RNA-dependent RNA polymerase (RdRp) residing in nonstructural protein 5B (NS5B), HCV isolates are grouped into seven genotypes with several subtypes. By using whole-genom...

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Detalles Bibliográficos
Autores principales: Fricke, Markus, Dünnes, Nadia, Zayas, Margarita, Bartenschlager, Ralf, Niepmann, Michael, Marz, Manja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478341/
https://www.ncbi.nlm.nih.gov/pubmed/25964384
http://dx.doi.org/10.1261/rna.049338.114

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