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Conserved RNA secondary structures and long-range interactions in hepatitis C viruses
Hepatitis C virus (HCV) is a hepatotropic virus with a plus-strand RNA genome of ∼9.600 nt. Due to error-prone replication by its RNA-dependent RNA polymerase (RdRp) residing in nonstructural protein 5B (NS5B), HCV isolates are grouped into seven genotypes with several subtypes. By using whole-genom...
Autores principales: | Fricke, Markus, Dünnes, Nadia, Zayas, Margarita, Bartenschlager, Ralf, Niepmann, Michael, Marz, Manja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478341/ https://www.ncbi.nlm.nih.gov/pubmed/25964384 http://dx.doi.org/10.1261/rna.049338.114 |
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