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DcpS is a transcript-specific modulator of RNA in mammalian cells

The scavenger decapping enzyme DcpS is a multifunctional protein initially identified by its property to hydrolyze the resulting cap structure following 3′ end mRNA decay. In Saccharomyces cerevisiae, the DcpS homolog Dcs1 is an obligate cofactor for the 5′-3′ exoribonuclease Xrn1 while the Caenorha...

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Detalles Bibliográficos
Autores principales: Zhou, Mi, Bail, Sophie, Plasterer, Heather L., Rusche, James, Kiledjian, Megerditch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478349/
https://www.ncbi.nlm.nih.gov/pubmed/26001796
http://dx.doi.org/10.1261/rna.051573.115