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Mutations that Separate the Functions of the Proofreading Subunit of the Escherichia coli Replicase
The dnaQ gene of Escherichia coli encodes the ε subunit of DNA polymerase III, which provides the 3′ → 5′ exonuclease proofreading activity of the replicative polymerase. Prior studies have shown that loss of ε leads to high mutation frequency, partially constitutive SOS, and poor growth. In additio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478557/ https://www.ncbi.nlm.nih.gov/pubmed/25878065 http://dx.doi.org/10.1534/g3.115.017285 |