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Development and validation of MCNPX-based Monte Carlo treatment plan verification system
A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the pat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478649/ https://www.ncbi.nlm.nih.gov/pubmed/26170554 http://dx.doi.org/10.4103/0971-6203.158678 |
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author | Jabbari, Iraj Monadi, Shahram |
author_facet | Jabbari, Iraj Monadi, Shahram |
author_sort | Jabbari, Iraj |
collection | PubMed |
description | A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the patient body. MCTPV has an interface with TiGRT planning system and reads the information which is needed for Monte Carlo calculation transferred in digital image communications in medicine-radiation therapy (DICOM-RT) format. In MCTPV several methods were applied in order to reduce the simulation time. The relative dose distribution of a clinical prostate conformal plan calculated by the MCTPV was compared with that of TiGRT planning system. The results showed well implementation of the beams configuration and patient information in this system. For quantitative evaluation of MCTPV a two-dimensional (2D) diode array (MapCHECK2) and gamma index analysis were used. The gamma passing rate (3%/3 mm) of an IMRT plan was found to be 98.5% for total beams. Also, comparison of the measured and Monte Carlo calculated doses at several points inside an inhomogeneous phantom for 6- and 18-MV photon beams showed a good agreement (within 1.5%). The accuracy and timing results of MCTPV showed that MCTPV could be used very efficiently for additional assessment of complicated plans such as IMRT plan. |
format | Online Article Text |
id | pubmed-4478649 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-44786492015-07-13 Development and validation of MCNPX-based Monte Carlo treatment plan verification system Jabbari, Iraj Monadi, Shahram J Med Phys Original Article A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the patient body. MCTPV has an interface with TiGRT planning system and reads the information which is needed for Monte Carlo calculation transferred in digital image communications in medicine-radiation therapy (DICOM-RT) format. In MCTPV several methods were applied in order to reduce the simulation time. The relative dose distribution of a clinical prostate conformal plan calculated by the MCTPV was compared with that of TiGRT planning system. The results showed well implementation of the beams configuration and patient information in this system. For quantitative evaluation of MCTPV a two-dimensional (2D) diode array (MapCHECK2) and gamma index analysis were used. The gamma passing rate (3%/3 mm) of an IMRT plan was found to be 98.5% for total beams. Also, comparison of the measured and Monte Carlo calculated doses at several points inside an inhomogeneous phantom for 6- and 18-MV photon beams showed a good agreement (within 1.5%). The accuracy and timing results of MCTPV showed that MCTPV could be used very efficiently for additional assessment of complicated plans such as IMRT plan. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4478649/ /pubmed/26170554 http://dx.doi.org/10.4103/0971-6203.158678 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jabbari, Iraj Monadi, Shahram Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title | Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title_full | Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title_fullStr | Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title_full_unstemmed | Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title_short | Development and validation of MCNPX-based Monte Carlo treatment plan verification system |
title_sort | development and validation of mcnpx-based monte carlo treatment plan verification system |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478649/ https://www.ncbi.nlm.nih.gov/pubmed/26170554 http://dx.doi.org/10.4103/0971-6203.158678 |
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