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Development and validation of MCNPX-based Monte Carlo treatment plan verification system

A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the pat...

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Autores principales: Jabbari, Iraj, Monadi, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478649/
https://www.ncbi.nlm.nih.gov/pubmed/26170554
http://dx.doi.org/10.4103/0971-6203.158678
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author Jabbari, Iraj
Monadi, Shahram
author_facet Jabbari, Iraj
Monadi, Shahram
author_sort Jabbari, Iraj
collection PubMed
description A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the patient body. MCTPV has an interface with TiGRT planning system and reads the information which is needed for Monte Carlo calculation transferred in digital image communications in medicine-radiation therapy (DICOM-RT) format. In MCTPV several methods were applied in order to reduce the simulation time. The relative dose distribution of a clinical prostate conformal plan calculated by the MCTPV was compared with that of TiGRT planning system. The results showed well implementation of the beams configuration and patient information in this system. For quantitative evaluation of MCTPV a two-dimensional (2D) diode array (MapCHECK2) and gamma index analysis were used. The gamma passing rate (3%/3 mm) of an IMRT plan was found to be 98.5% for total beams. Also, comparison of the measured and Monte Carlo calculated doses at several points inside an inhomogeneous phantom for 6- and 18-MV photon beams showed a good agreement (within 1.5%). The accuracy and timing results of MCTPV showed that MCTPV could be used very efficiently for additional assessment of complicated plans such as IMRT plan.
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spelling pubmed-44786492015-07-13 Development and validation of MCNPX-based Monte Carlo treatment plan verification system Jabbari, Iraj Monadi, Shahram J Med Phys Original Article A Monte Carlo treatment plan verification (MCTPV) system was developed for clinical treatment plan verification (TPV), especially for the conformal and intensity-modulated radiotherapy (IMRT) plans. In the MCTPV, the MCNPX code was used for particle transport through the accelerator head and the patient body. MCTPV has an interface with TiGRT planning system and reads the information which is needed for Monte Carlo calculation transferred in digital image communications in medicine-radiation therapy (DICOM-RT) format. In MCTPV several methods were applied in order to reduce the simulation time. The relative dose distribution of a clinical prostate conformal plan calculated by the MCTPV was compared with that of TiGRT planning system. The results showed well implementation of the beams configuration and patient information in this system. For quantitative evaluation of MCTPV a two-dimensional (2D) diode array (MapCHECK2) and gamma index analysis were used. The gamma passing rate (3%/3 mm) of an IMRT plan was found to be 98.5% for total beams. Also, comparison of the measured and Monte Carlo calculated doses at several points inside an inhomogeneous phantom for 6- and 18-MV photon beams showed a good agreement (within 1.5%). The accuracy and timing results of MCTPV showed that MCTPV could be used very efficiently for additional assessment of complicated plans such as IMRT plan. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4478649/ /pubmed/26170554 http://dx.doi.org/10.4103/0971-6203.158678 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jabbari, Iraj
Monadi, Shahram
Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title_full Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title_fullStr Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title_full_unstemmed Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title_short Development and validation of MCNPX-based Monte Carlo treatment plan verification system
title_sort development and validation of mcnpx-based monte carlo treatment plan verification system
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478649/
https://www.ncbi.nlm.nih.gov/pubmed/26170554
http://dx.doi.org/10.4103/0971-6203.158678
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