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High level of chromosomal instability in circulating tumor cells of ROS1-rearranged non-small-cell lung cancer
BACKGROUND: Genetic aberrations affecting the c-ros oncogene 1 (ROS1) tyrosine kinase gene have been reported in a small subset of patients with non-small-cell lung cancer (NSCLC). We evaluated whether ROS1-chromosomal rearrangements could be detected in circulating tumor cells (CTCs) and examined t...
Autores principales: | Pailler, E., Auger, N., Lindsay, C. R., Vielh, P., Islas-Morris-Hernandez, A., Borget, I., Ngo-Camus, M., Planchard, D., Soria, J.-C., Besse, B., Farace, F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478971/ https://www.ncbi.nlm.nih.gov/pubmed/25846554 http://dx.doi.org/10.1093/annonc/mdv165 |
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