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Allele-specific analysis of DNA replication origins in mammalian cells

The mechanisms that control the location and timing of firing of replication origins are poorly understood. Using a novel functional genomic approach based on the analysis of SNPs and indels in phased human genomes, we observe that replication asynchrony is associated with small cumulative variation...

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Detalles Bibliográficos
Autores principales:	Bartholdy, Boris, Mukhopadhyay, Rituparna, Lajugie, Julien, Aladjem, Mirit I., Bouhassira, Eric E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479011/ https://www.ncbi.nlm.nih.gov/pubmed/25987481 http://dx.doi.org/10.1038/ncomms8051

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