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Atomistic design of microbial opsin-based blue-shifted optogenetics tools
Microbial opsins with a bound chromophore function as photosensitive ion transporters and have been employed in optogenetics for the optical control of neuronal activity. Molecular engineering has been utilized to create colour variants for the functional augmentation of optogenetics tools, but was...
Autores principales: | Kato, Hideaki E., Kamiya, Motoshi, Sugo, Seiya, Ito, Jumpei, Taniguchi, Reiya, Orito, Ayaka, Hirata, Kunio, Inutsuka, Ayumu, Yamanaka, Akihiro, Maturana, Andrés D., Ishitani, Ryuichiro, Sudo, Yuki, Hayashi, Shigehiko, Nureki, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479019/ https://www.ncbi.nlm.nih.gov/pubmed/25975962 http://dx.doi.org/10.1038/ncomms8177 |
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