Cargando…
Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance
Unrelenting environmental challenges to the gut epithelium place particular demands on the local immune system. In this context, intestinal intraepithelial lymphocytes (IEL) compose a large, highly conserved T cell compartment, hypothesized to provide a first line of defence via cytolysis of dysregu...
Autores principales: | Swamy, Mahima, Abeler-Dörner, Lucie, Chettle, James, Mahlakõiv, Tanel, Goubau, Delphine, Chakravarty, Probir, Ramsay, George, Reis e Sousa, Caetano, Staeheli, Peter, Blacklaws, Barbara A., Heeney, Jonathan L., Hayday, Adrian C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479038/ https://www.ncbi.nlm.nih.gov/pubmed/25987506 http://dx.doi.org/10.1038/ncomms8090 |
Ejemplares similares
-
Mechanisms of activation of innate-like intraepithelial T lymphocytes
por: Vandereyken, Maud, et al.
Publicado: (2020) -
SS7-3 A non-redundant role of IFN-λ in antiviral defense of the intestinal tract
por: Mordstein, Markus, et al.
Publicado: (2010) -
Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections
por: Mahlakõiv, Tanel, et al.
Publicado: (2015) -
Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo
por: Hermant, Pascale, et al.
Publicado: (2014) -
Mouse superkiller‐2‐like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses
por: Goubau, Delphine, et al.
Publicado: (2015)