Cargando…

In silico inhibition of GABARAP activity using antiepileptic medicinal derived compounds

Epilepsy is a neurological disorder affecting more than 50 million people worldwide. It can be controlled by antiepileptic drugs (AEDs) but more than 30% patients are still resistant to AEDs. To overcome this problem, researchers are trying to develop novel approaches to treat epilepsy including the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathew, Shilu, Faheem, Muhammad, Al-Malki, Abdulrahman L, Kumosani, Taha A, Qadri, Ishtiaq
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2015
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479051/ https://www.ncbi.nlm.nih.gov/pubmed/26124559 http://dx.doi.org/10.6026/97320630011189

Ejemplares similares

In Silico Studies of Medicinal Compounds Against Hepatitis C Capsid Protein from North India
por: Mathew, Shilu, et al.
Publicado: (2014)

Molecular designing and in silico evaluation of darunavir derivatives as anticancer agents
por: Mahto, Manoj kumar, et al.
Publicado: (2014)

in Silico investigation of the structural requirements for the AMPA receptor antagonism by quinoxaline derivatives
por: Azam, Faizul, et al.
Publicado: (2013)

Virtual screening of plant derived compounds for aldose reductase inhibition using molecular docking
por: Muppalaneni, Naresh Babu, et al.
Publicado: (2012)

Molecular modeling of Ruellia tuberosa L compounds as a-amylase inhibitor: an in silico comparation between human and rat enzyme model
por: Wulan, Dyah Ratna, et al.
Publicado: (2014)

Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
por: Joachim, Justin, et al.
Publicado: (2017)

In silico analysis of Myoglobin in Channa striata
por: Parveen, Farzana, et al.
Publicado: (2014)

In silico pharmacokinetic and molecular docking studies of small molecules derived from Indigofera aspalathoides Vahl targeting receptor tyrosine kinases
por: Paramashivam, Sathish Kumar, et al.
Publicado: (2015)

Molecular docking based screening of neem-derived compounds with the NS1 protein of Influenza virus
por: Ahmad, Aftab, et al.
Publicado: (2015)

An in silico approach to map the binding site of doxorubicin on hemoglobin
por: Khan, Shahper Nazeer, et al.
Publicado: (2008)

In silico analysis of onion chitinases using transcriptome data
por: Mohapatra, Rupesh Kumar, et al.
Publicado: (2018)

In Silico Validation of D7 Salivary Protein-derived B- and T-cell Epitopes of Aedes aegypti as Potential Vaccine to Prevent Transmission of Flaviviruses and Togaviruses to Humans
por: Sankar, Sathish, et al.
Publicado: (2017)

Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone
por: Sarmah, Rajeev
Publicado: (2012)

In silico studies on marine actinomycetes as potential inhibitors for Glioblastoma multiforme
por: Kirubakaran, Palani, et al.
Publicado: (2011)

in-silico study of arylalkylamine-nacetyltransferase enzyme to regulate circadian rhythmicity
por: Prashant, Kumar, et al.
Publicado: (2013)

in silico identification of protein-protein interactions in Silkworm, Bombyx mori
por: Sumathy, Ramasamy, et al.
Publicado: (2014)

The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles
por: Sanwald, Julia L., et al.
Publicado: (2020)

Computer aided screening of potent inhibitor compounds against inhibitor resistant TEM β-lactamase mutants from traditional Chinese medicine
por: Zhu, Qifeng, et al.
Publicado: (2014)

Role of nitric oxide synthase in insect cell radioresistance: an in-silico analysis
por: Suman, Shubhankar, et al.
Publicado: (2008)

In-silico comparative study of inhibitory mechanism of Plant Serine Proteinase Inhibitors
por: Siva Prasad, Chekkara Venkata Sathya, et al.
Publicado: (2012)

in silico-prediction of downstream WRKY interacting partners of MAPK3 in Brassica
por: Giri, Priyanka, et al.
Publicado: (2013)

Comparison of simple sequence repeats in Staphylococcus strains using in-silico approach
por: Thorat, Sunil, et al.
Publicado: (2012)

In silico-prediction of downstream MYB interacting partners of MAPK3 in Arabidopsis
por: Giri, Priyanka, et al.
Publicado: (2014)

In-Vitro and in-Silico characterization of Sophora interrupta plant extract as an anticancer activity
por: Mathi, Pardhasaradhi, et al.
Publicado: (2014)

Screening and design of anti-diabetic compounds sourced from the leaves of neem (Azadirachta indica)
por: Jalil, Asma, et al.
Publicado: (2013)

Genetic diversity and species pattern of Trichoderma and Hypocrea in Manipur using in silico analysis
por: Kamala, Thongram, et al.
Publicado: (2013)

In silico characterization of putative drug targets in Staphylococcus saprophyticus, causing bovine mastitis
por: Bhasme, Pramod C, et al.
Publicado: (2013)

In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in Staphylococcus saprophyticus
por: Shahid, Farah, et al.
Publicado: (2020)

Influence of PCOS in Obese vs. Non-Obese women from Mesenchymal Progenitors Stem Cells and Other Endometrial Cells: An in silico biomarker discovery
por: Desai, Ashvini, et al.
Publicado: (2017)

Virtual screening of compounds from the patchouli oil of Pogostemon herba for COX-1 inhibition
por: Raharjo, Sentot Joko, et al.
Publicado: (2013)

Molecular docking based virtual screening of compounds for inhibiting sortase A in L.monocytogenes
por: Rashidieh, Behnam, et al.
Publicado: (2015)

In silico identification of miRNAs and their targets from the expressed sequence tags of Raphanus sativus
por: Muvva, Charuvaka, et al.
Publicado: (2012)

In silico characterization of a RNA binding protein of cattle filarial parasite Setaria digitata
por: Nagaratnam, Nirupa, et al.
Publicado: (2014)

Agonistic approach of omega-3, omega-6 and its metabolites with BDNF: An in-silico study
por: Kumar, Yadla Phani, et al.
Publicado: (2013)

Understanding mechanism of in vitro maturation, fertilization and culture of sheep embryoes through in silico analysis
por: Sreenivas, Dulam, et al.
Publicado: (2012)

Piroxicam confer neuroprotection in Cerebral Ischemia by inhibiting Cyclooxygenases, Acid- Sensing Ion Channel-1a and Aquaporin-4: an in silico comparison with Aspirin and Nimesulide
por: Mazumder, Muhammed Khairujjaman, et al.
Publicado: (2015)

In silico modeling of ligand molecule for non structural 3 (NS3) protein target of flaviviruses
por: Agnihotri, Shefali, et al.
Publicado: (2012)

Sequence analysis, structure and binding site prediction of Sigma 1 receptor protein by in silico method
por: Latha, Narayanasamy Lokeswaran, et al.
Publicado: (2013)

A Hypothesis: Supplementation with Mushroom-Derived Active Compound Modulates Immunity and Increases Survival in Response to Influenza Virus (H1N1) Infection
por: Chunchao, Han, et al.
Publicado: (2011)

In-silico screening and in-vitro validation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) inhibitors
por: Saraswat, Deepika, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_prvnkrnae7670nev1kfhjvbqri