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BlastXtract2: Improving early exploration of (meta) genomes
To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479055/ https://www.ncbi.nlm.nih.gov/pubmed/26124555 http://dx.doi.org/10.6026/97320630011173 |
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author | de Weerd, Heleen van der Veen, Bernd E Claesson, Marcus J |
author_facet | de Weerd, Heleen van der Veen, Bernd E Claesson, Marcus J |
author_sort | de Weerd, Heleen |
collection | PubMed |
description | To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences. AVAILABILITY: Source code, documentation and an online demo version are available at https://github.com/ ClaessonLab/BlastXtract2 |
format | Online Article Text |
id | pubmed-4479055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-44790552015-06-29 BlastXtract2: Improving early exploration of (meta) genomes de Weerd, Heleen van der Veen, Bernd E Claesson, Marcus J Bioinformation Database To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences. AVAILABILITY: Source code, documentation and an online demo version are available at https://github.com/ ClaessonLab/BlastXtract2 Biomedical Informatics 2015-04-30 /pmc/articles/PMC4479055/ /pubmed/26124555 http://dx.doi.org/10.6026/97320630011173 Text en © 2015 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Database de Weerd, Heleen van der Veen, Bernd E Claesson, Marcus J BlastXtract2: Improving early exploration of (meta) genomes |
title | BlastXtract2: Improving early exploration of (meta) genomes |
title_full | BlastXtract2: Improving early exploration of (meta) genomes |
title_fullStr | BlastXtract2: Improving early exploration of (meta) genomes |
title_full_unstemmed | BlastXtract2: Improving early exploration of (meta) genomes |
title_short | BlastXtract2: Improving early exploration of (meta) genomes |
title_sort | blastxtract2: improving early exploration of (meta) genomes |
topic | Database |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479055/ https://www.ncbi.nlm.nih.gov/pubmed/26124555 http://dx.doi.org/10.6026/97320630011173 |
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