Cargando…
Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis
BACKGROUND: Saturated fatty acids are toxic to liver cells and are believed to play a central role in the pathogenesis of non-alcoholic steatohepatitis. In experimental steatohepatitis induced by feeding mice a methionine-choline-deficient (MCD) diet, the degree of liver damage is related to dietary...
Autores principales: | Pierce, Andrew A., Pickens, Michael K., Siao, Kevin, Grenert, James P., Maher, Jacquelyn J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479079/ https://www.ncbi.nlm.nih.gov/pubmed/26103964 http://dx.doi.org/10.1186/s12876-015-0298-y |
Ejemplares similares
-
Osteoprotegerin deficiency aggravates methionine–choline-deficient diet-induced nonalcoholic steatohepatitis in mice
por: Wu, Shaobo, et al.
Publicado: (2023) -
Role of adipose tissue in methionine–choline-deficient model of non-alcoholic steatohepatitis (NASH)()
por: Jha, Pooja, et al.
Publicado: (2014) -
Γ-Aminobutyric acid promotes methionine-choline deficient diet-induced nonalcoholic steatohepatitis
por: Seok Roh, Yoon, et al.
Publicado: (2017) -
CD18 deficiency improves liver injury in the MCD model of steatohepatitis
por: Pierce, Andrew A., et al.
Publicado: (2017) -
Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood
por: Du, Juan, et al.
Publicado: (2018)