Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment

Xihuang pill (XH) is a complementary and alternative medicine that has been used in traditional Chinese medicine (TCM) for the treatment of tumors since the 18th century. XH has clinical effects on non-Hodgkin lymphoma, breast cancer, gastric cancer, liver cancer, and bone metastasis. XH can also in...

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Autores principales: Guo, Qiujun, Lin, Jinyin, Liu, Rui, Gao, Yebo, He, Shulin, Xu, Xinyao, Hua, Baojin, Li, Conghuang, Hou, Wei, Zheng, Honggang, Bao, Yanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479127/
https://www.ncbi.nlm.nih.gov/pubmed/26170886
http://dx.doi.org/10.1155/2015/854307
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author Guo, Qiujun
Lin, Jinyin
Liu, Rui
Gao, Yebo
He, Shulin
Xu, Xinyao
Hua, Baojin
Li, Conghuang
Hou, Wei
Zheng, Honggang
Bao, Yanju
author_facet Guo, Qiujun
Lin, Jinyin
Liu, Rui
Gao, Yebo
He, Shulin
Xu, Xinyao
Hua, Baojin
Li, Conghuang
Hou, Wei
Zheng, Honggang
Bao, Yanju
author_sort Guo, Qiujun
collection PubMed
description Xihuang pill (XH) is a complementary and alternative medicine that has been used in traditional Chinese medicine (TCM) for the treatment of tumors since the 18th century. XH has clinical effects on non-Hodgkin lymphoma, breast cancer, gastric cancer, liver cancer, and bone metastasis. XH can also inhibit the growth of tumor cells and cancer stem cells, prevent tumor invasion and angiogenesis, and regulate the tumor microenvironment. XH is composed of Ru Xiang (olibanum), Mo Yao (Commiphora myrrha), She Xiang (Moschus), and Niu Huang (Calculus bovis). Some of the compounds found in these ingredients exert multiple antitumor effects and may synergize with the other ingredients. We aimed to summarize the clinical applications and molecular mechanisms of XH and its chemical composition. This review will provide potential new strategies and alternative perspectives for tumor treatments and basic research into complementary and alternative medicine.
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spelling pubmed-44791272015-07-13 Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment Guo, Qiujun Lin, Jinyin Liu, Rui Gao, Yebo He, Shulin Xu, Xinyao Hua, Baojin Li, Conghuang Hou, Wei Zheng, Honggang Bao, Yanju Evid Based Complement Alternat Med Review Article Xihuang pill (XH) is a complementary and alternative medicine that has been used in traditional Chinese medicine (TCM) for the treatment of tumors since the 18th century. XH has clinical effects on non-Hodgkin lymphoma, breast cancer, gastric cancer, liver cancer, and bone metastasis. XH can also inhibit the growth of tumor cells and cancer stem cells, prevent tumor invasion and angiogenesis, and regulate the tumor microenvironment. XH is composed of Ru Xiang (olibanum), Mo Yao (Commiphora myrrha), She Xiang (Moschus), and Niu Huang (Calculus bovis). Some of the compounds found in these ingredients exert multiple antitumor effects and may synergize with the other ingredients. We aimed to summarize the clinical applications and molecular mechanisms of XH and its chemical composition. This review will provide potential new strategies and alternative perspectives for tumor treatments and basic research into complementary and alternative medicine. Hindawi Publishing Corporation 2015 2015-06-10 /pmc/articles/PMC4479127/ /pubmed/26170886 http://dx.doi.org/10.1155/2015/854307 Text en Copyright © 2015 Qiujun Guo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Guo, Qiujun
Lin, Jinyin
Liu, Rui
Gao, Yebo
He, Shulin
Xu, Xinyao
Hua, Baojin
Li, Conghuang
Hou, Wei
Zheng, Honggang
Bao, Yanju
Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title_full Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title_fullStr Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title_full_unstemmed Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title_short Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment
title_sort review on the applications and molecular mechanisms of xihuang pill in tumor treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479127/
https://www.ncbi.nlm.nih.gov/pubmed/26170886
http://dx.doi.org/10.1155/2015/854307
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