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Tuning the Attempt Frequency of Protein Folding Dynamics via Transition-State Rigidification: Application to Trp-Cage
[Image: see text] The attempt frequency or prefactor (k(0)) of the transition-state rate equation of protein folding kinetics has been estimated to be on the order of 10(6) s(–1), which is many orders of magnitude smaller than that of chemical reactions. Herein we use the mini-protein Trp-cage to sh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479204/ https://www.ncbi.nlm.nih.gov/pubmed/26120378 http://dx.doi.org/10.1021/jz502654q |