Prediction of complex human diseases from pathway-focused candidate markers by joint estimation of marker effects: case of chronic fatigue syndrome

BACKGROUND: The current practice of using only a few strongly associated genetic markers in regression models results in generally low power in prediction or accounting for heritability of complex human traits. PURPOSE: We illustrate here a Bayesian joint estimation of single nucleotide polymorphism...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Madhuchhanda, Rajeevan, Mangalathu S., Sillanpää, Mikko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479222/
https://www.ncbi.nlm.nih.gov/pubmed/26063326
http://dx.doi.org/10.1186/s40246-015-0030-6

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