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Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment

BACKGROUND: Cerebral infarction due to thrombosis leads to the most common type of stroke and a likely cause of age-related cognitive decline and dementia. Endothelial nitric oxide synthase (eNOS) generates NO, which plays a crucial role in maintaining vascular function and exerting an antithromboti...

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Detalles Bibliográficos
Autores principales: Tan, Xing-Lin, Xue, Yue-Qiang, Ma, Tao, Wang, Xiaofang, Li, Jing Jing, Lan, Lubin, Malik, Kafait U., McDonald, Michael P., Dopico, Alejandro M., Liao, Francesca-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479241/
https://www.ncbi.nlm.nih.gov/pubmed/26104027
http://dx.doi.org/10.1186/s13024-015-0020-0