The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif autophagic degradation

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its viral infectivity factor (Vif), a key protein for HIV-1 infectivity and in vivo pathogenesis. Vif interacts with and promotes “apo...

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Detalles Bibliográficos
Autores principales: Valera, María-Soledad, de Armas-Rillo, Laura, Barroso-González, Jonathan, Ziglio, Serena, Batisse, Julien, Dubois, Noé, Marrero-Hernández, Sara, Borel, Sophie, García-Expósito, Laura, Biard-Piechaczyk, Martine, Paillart, Jean-Christophe, Valenzuela-Fernández, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479245/
https://www.ncbi.nlm.nih.gov/pubmed/26105074
http://dx.doi.org/10.1186/s12977-015-0181-5

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