Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice

Diabetes mellitus-associated damage to the microvasculature of the brain is caused by hyperglycemia-induced oxidative stress, which results in pericyte loss, blood-brain barrier disruption, and impaired cognitive function. Oxidative stress, in diabetes, is caused by reactive oxygen species produced...

Descripción completa

Detalles Bibliográficos
Autores principales: Price, Tulin O., Farr, Susan A., Niehoff, Michael L., Ercal, Nuran, Morley, John E., Shah, Gul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479302/
https://www.ncbi.nlm.nih.gov/pubmed/26120599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479302/
https://www.ncbi.nlm.nih.gov/pubmed/26120599

Ejemplares similares