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Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids

Elevated levels of lipoprotein (a) [Lp(a)] are a well-established risk factor for developing CVD. While Lp(a) levels are thought to be independent of other plasma lipoproteins, some trials have reported a positive association between Lp(a) and HDL. Whether Lp(a) has a direct effect on HDL is not kno...

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Detalles Bibliográficos
Autores principales: Sharma, Monika, Von Zychlinski-Kleffmann, Anne, Porteous, Carolyn M., Jones, Gregory T., Williams, Michael J. A., McCormick, Sally P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479336/
https://www.ncbi.nlm.nih.gov/pubmed/25852127
http://dx.doi.org/10.1194/jlr.M056150

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