Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans

BACKGROUND: Mitochondrial alterations have been observed in subjects with metabolic disorders such as obesity and diabetes. Studies on animal models and cell cultures suggest aberrant glucose and lipid levels, and impaired insulin signaling might lead to mitochondrial changes. However, the molecular...

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Detalles Bibliográficos
Autores principales: Zheng, Louise D., Linarelli, Leah E., Liu, Longhua, Wall, Sarah S., Greenawald, Mark H., Seidel, Richard W., Estabrooks, Paul A., Almeida, Fabio A., Cheng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479353/
https://www.ncbi.nlm.nih.gov/pubmed/26110043
http://dx.doi.org/10.1186/s13148-015-0093-1

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