Alzheimer’s loci: epigenetic associations and interaction with genetic factors

OBJECTIVE: We explore the role of DNA methylation in Alzheimer’s disease (AD). To elucidate where DNA methylation falls along the causal pathway linking risk factors to disease, we examine causal models to assess its role in the pathology of AD. METHODS: DNA methylation profiles were generated in 74...

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Detalles Bibliográficos
Autores principales: Chibnik, Lori B, Yu, Lei, Eaton, Matthew L, Srivastava, Gyan, Schneider, Julie A, Kellis, Manolis, Bennett, David A, De Jager, Philip L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479524/
https://www.ncbi.nlm.nih.gov/pubmed/26125039
http://dx.doi.org/10.1002/acn3.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479524/
https://www.ncbi.nlm.nih.gov/pubmed/26125039
http://dx.doi.org/10.1002/acn3.201

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