Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia

Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus palli...

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Autores principales: Ramos, Vesper Fe Marie L, Pillai, Ajay S, Lungu, Codrin, Ostrem, Jill, Starr, Philip, Hallett, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479530/
https://www.ncbi.nlm.nih.gov/pubmed/26125045
http://dx.doi.org/10.1002/acn3.206
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author Ramos, Vesper Fe Marie L
Pillai, Ajay S
Lungu, Codrin
Ostrem, Jill
Starr, Philip
Hallett, Mark
author_facet Ramos, Vesper Fe Marie L
Pillai, Ajay S
Lungu, Codrin
Ostrem, Jill
Starr, Philip
Hallett, Mark
author_sort Ramos, Vesper Fe Marie L
collection PubMed
description Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus pallidus internus were retrospectively compared with those of five patients with known DYT1 dystonia using spontaneous discharge parameters of rate and bursting, as well as movement-related discharges. Our data suggest that simple intraoperative neurophysiology measures in single subjects do not differentiate psychogenic dystonia from DYT1 dystonia.
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spelling pubmed-44795302015-06-29 Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia Ramos, Vesper Fe Marie L Pillai, Ajay S Lungu, Codrin Ostrem, Jill Starr, Philip Hallett, Mark Ann Clin Transl Neurol Brief Communications Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus pallidus internus were retrospectively compared with those of five patients with known DYT1 dystonia using spontaneous discharge parameters of rate and bursting, as well as movement-related discharges. Our data suggest that simple intraoperative neurophysiology measures in single subjects do not differentiate psychogenic dystonia from DYT1 dystonia. John Wiley & Sons, Ltd 2015-06 2015-04-17 /pmc/articles/PMC4479530/ /pubmed/26125045 http://dx.doi.org/10.1002/acn3.206 Text en © 2015 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Brief Communications
Ramos, Vesper Fe Marie L
Pillai, Ajay S
Lungu, Codrin
Ostrem, Jill
Starr, Philip
Hallett, Mark
Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title_full Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title_fullStr Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title_full_unstemmed Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title_short Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
title_sort intraoperative neurophysiology in deep brain surgery for psychogenic dystonia
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479530/
https://www.ncbi.nlm.nih.gov/pubmed/26125045
http://dx.doi.org/10.1002/acn3.206
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