Cargando…

Effect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV Infection

OBJECTIVES: The main aim of this study was to investigate the effect of CYP2B6 gene polymorphisms on efavirenz (EFV) plasma concentrations in Han Chinese patients with human immunodeficiency virus (HIV) infection. METHODS: In total, 322 patients were recruited for study. EFV plasma concentrations at...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Xianmin, Yin, Kang, Wang, Jiangrong, Dong, Ping, Liu, Li, Shen, Yinzhong, Shen, Li, Ma, Qing, Lu, Hongzhou, Cai, Weimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479596/ https://www.ncbi.nlm.nih.gov/pubmed/26107645 http://dx.doi.org/10.1371/journal.pone.0130583

Ejemplares similares

Impact of CYP2B6 and CYP2A6 polymorphisms on efavirenz plasma concentrations in Ghanaian HIV-infected patients
por: Zhang, Y, et al.
Publicado: (2010)

Efficacy of Efavirenz-Based Regimen in Antiretroviral-Naïve Patients with HIV-1 V179D/E Mutations in Shanghai, China
por: Wang, Zhenyan, et al.
Publicado: (2022)

Analysis of the immunologic status of a newly diagnosed HIV positive population in China
por: Shen, Yinzhong, et al.
Publicado: (2013)

Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China
por: Wang, Zhenyan, et al.
Publicado: (2019)

Dose Optimization of Efavirenz Based on Individual CYP2B6 Polymorphisms in Chinese Patients Positive for HIV
por: Hui, KH, et al.
Publicado: (2016)

Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial
por: Chen, Jun, et al.
Publicado: (2020)

Prevalence of Anemia among Adults with Newly Diagnosed HIV/AIDS in China
por: Shen, Yinzhong, et al.
Publicado: (2013)

Prediction of plasma efavirenz concentrations among HIV-positive patients taking efavirenz-containing combination antiretroviral therapy
por: Huang, Sung-Hsi, et al.
Publicado: (2017)

Interferon-Gamma Release Assays for the Diagnosis of Active Tuberculosis in HIV-Infected Patients: A Systematic Review and Meta-Analysis
por: Chen, Jun, et al.
Publicado: (2011)

Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients
por: Gounden, Verena, et al.
Publicado: (2010)

Discovery of Potential Plasma Biomarkers for Tuberculosis in HIV-Infected Patients by Data-Independent Acquisition-Based Quantitative Proteomics
por: Shen, Yinzhong, et al.
Publicado: (2020)

Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans
por: Johnston, Jenna, et al.
Publicado: (2019)

Plasma Efavirenz Concentrations Are Associated With Lipid and Glucose Concentrations
por: Sinxadi, Phumla Zuleika, et al.
Publicado: (2016)

Prevalence of Dyslipidemia Among Antiretroviral-Naive HIV-Infected Individuals in China
por: Shen, Yinzhong, et al.
Publicado: (2015)

Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients
por: Chamnanphon, Monpat, et al.
Publicado: (2021)

Genetic variants in CYP2B6 and CYP2A6 explain interindividual variation in efavirenz plasma concentrations of HIV-infected children with diverse ethnic origin
por: Soeria-Atmadja, Sandra, et al.
Publicado: (2017)

Spectrum of Opportunistic Infections and Risk Factors for In-Hospital Mortality of Admitted AIDS Patients in Shanghai
por: Luo, Bin, et al.
Publicado: (2016)

Gut Microbiota Dysbiosis Is Not Independently Associated With Neurocognitive Impairment in People Living With HIV
por: Zhang, Fengdi, et al.
Publicado: (2019)

Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania
por: Sungi, Selemani Saidi, et al.
Publicado: (2018)

Role of efavirenz plasma concentrations on long-term HIV suppression and immune restoration in HIV-infected children
por: Homkham, Nontiya, et al.
Publicado: (2019)

Large variability in plasma efavirenz concentration in Papua New Guinea HIV/AIDS patients associated with high frequency of CYP2B6 516T allele
por: Bordin Andriguetti, Natália, et al.
Publicado: (2021)

Constitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity
por: Petros, Zelalem, et al.
Publicado: (2022)

Association between social psychological status and efavirenz and nevirapine plasma concentration among HIV patients in Kenya
por: Ngayo, Musa Otieno, et al.
Publicado: (2021)

Evaluation of an immunoassay for determination of plasma efavirenz concentrations in resource-limited settings
por: Abdissa, Alemseged, et al.
Publicado: (2014)

CYP46A1-dependent and independent effects of efavirenz treatment
por: Mast, Natalia, et al.
Publicado: (2020)

Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults
por: Uttayamakul, Sumonmal, et al.
Publicado: (2010)

Efavirenz, dysrhythmia and HIV
por: Mungmunpuntipantip, Rujittika, et al.
Publicado: (2021)

Circulating (1 → 3)-β-D-Glucan as an immune activation marker decreased after ART in people living with HIV
por: Xun, Jingna, et al.
Publicado: (2022)

PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients
por: Swart, Marelize, et al.
Publicado: (2012)

Prevalence of hyperglycemia among adults with newly diagnosed HIV/AIDS in China
por: Shen, Yinzhong, et al.
Publicado: (2013)

Pandemic (H1N1) 2009, Shanghai, China
por: Shen, Yinzhong, et al.
Publicado: (2010)

Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog
por: Shah, Manish B., et al.
Publicado: (2018)

Clinical characteristics and risk factors for poor prognosis among HIV patients with Talaromyces marneffei bloodstream infection
por: Sun, Jianjun, et al.
Publicado: (2021)

Dyslipidaemia and Intima-Media Thickness of Carotid Arteries in Thirty-Five HIV/AIDS Patients Receiving Highly Active Antiretroviral Therapy
por: Zhang, Xuexiang, et al.
Publicado: (2009)

Anti-Retroviral Therapy Decreases but Does Not Normalize Indoleamine 2,3-Dioxygenase Activity in HIV-Infected Patients
por: Chen, Jun, et al.
Publicado: (2014)

The Effects of Cumulative Dose and Polymorphisms in CYP2B6 on the Mitotane Plasma Trough Concentrations in Chinese Patients With Advanced Adrenocortical Carcinoma
por: Liu, Xin, et al.
Publicado: (2022)

Changes in intestinal microbiota in HIV-1-infected subjects following cART initiation: influence of CD4+ T cell count
por: Ji, Yongjia, et al.
Publicado: (2018)

Associations between efavirenz concentrations, pharmacogenetics and neurocognitive performance in people living with HIV in Nigeria
por: Nwogu, Jacinta N., et al.
Publicado: (2021)

Long-term case-fatality rate of nontuberculous mycobacterial disease in people living with HIV
por: Hu, Jingjing, et al.
Publicado: (2022)

Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone
por: Lu, Jinjun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7u0i9ob0qf1agh2n6c08qlqqcq