Cargando…

Combination Therapy for Gliomas Using Temozolomide and Interferon-Beta Secreting Human Bone Marrow Derived Mesenchymal Stem Cells

OBJECTIVE: Malignant gliomas are the most common primary tumors of the central nervous system and the prognosis of patients with gliomas is poor. The combination of interferon-bata (IFN-β) and temozolomide (TMZ) has shown significant additive antitumor effects in human glioma xenograft models. Consi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Jae-Hyun, Ryu, Chung Heon, Kim, Mi Jin, Jeun, Sin-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Neurosurgical Society 2015
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479712/ https://www.ncbi.nlm.nih.gov/pubmed/26113958 http://dx.doi.org/10.3340/jkns.2015.57.5.323

Ejemplares similares

Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells
por: Yoon, Wan-Soo, et al.
Publicado: (2017)

Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma
por: Shao, Naiyuan, et al.
Publicado: (2018)

Gene Therapy of Multiple Sclerosis Using Interferon β-Secreting Human Bone Marrow Mesenchymal Stem Cells
por: Ryu, Chung Heon, et al.
Publicado: (2013)

Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma
por: Bikhezar, Fatima, et al.
Publicado: (2019)

Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide
por: Sun, Stella, et al.
Publicado: (2012)

Identification of two distinct mesenchymal stromal cell populations in human malignant glioma
por: Svensson, Andreas, et al.
Publicado: (2016)

Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1
por: Gallitto, Matthew, et al.
Publicado: (2020)

The Dose Dependent Effects of Ruxolitinib on the Invasion and Tumorigenesis in Gliomas Cells via Inhibition of Interferon Gamma-Depended JAK/STAT Signaling Pathway
por: Delen, Emre, et al.
Publicado: (2020)

The Formation of Extragraft Bone Bridging after Anterior Cervical Discectomy and Fusion: A Finite Element Analysis
por: Kwon, Shin Won, et al.
Publicado: (2017)

Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells
por: Komakech, Alfred, et al.
Publicado: (2020)

A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia
por: Musah-Eroje, Ahmed, et al.
Publicado: (2019)

Overexpressions of Vimentin and Integrins in Human Metastatic Spine Tumors
por: Park, Sung Bae, et al.
Publicado: (2015)

Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit
por: Castro, Michael, et al.
Publicado: (2021)

Bacitracin Inhibits the Migration of U87-MG Glioma Cells via Interferences of the Integrin Outside-in Signaling Pathway
por: Li, Songyuan, et al.
Publicado: (2016)

Metallothinein 1E Enhances Glioma Invasion through Modulation Matrix Metalloproteinases-2 and 9 in U87MG Mouse Brain Tumor Model
por: Hur, Hyuk, et al.
Publicado: (2016)

Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
por: Ryu, Chung Heon, et al.
Publicado: (2012)

Isthmin inhibits glioma growth through antiangiogenesis in vivo
por: Yuan, Bangqing, et al.
Publicado: (2012)

Targeting Orthotopic Glioma in Mice with Genetically Engineered Salmonella typhimurium
por: Wen, Min, et al.
Publicado: (2014)

Intra-Spinal Bone Marrow Mononuclear Cells Transplantation Inhibits the Expression of Nuclear Factor-κB in Acute Transection Spinal Cord Injury in Rats
por: Shrestha, Rajiv Prasad, et al.
Publicado: (2014)

IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat
por: Sears, Thomas K., et al.
Publicado: (2021)

Polycomb-like 2 regulates PRC2 components to affect proliferation in glioma cells
por: Wang, Fei, et al.
Publicado: (2020)

EID3 Promotes Glioma Cell Proliferation and Survival by Inactivating AMPKα1
por: Xiang, Yaoxian, et al.
Publicado: (2022)

Role of a Burr Hole and Calvarial Bone Marrow-Derived Stem Cells in the Ischemic Rat Brain: A Possible Mechanism for the Efficacy of Multiple Burr Hole Surgery in Moyamoya Disease
por: Nam, Taek-kyun, et al.
Publicado: (2015)

Difference in Spinal Fusion Process in Osteopenic and Nonosteopenic Living Rat Models Using Serial Microcomputed Tomography
por: Park, Sung Bae, et al.
Publicado: (2017)

Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1
por: Liu, Jinlong, et al.
Publicado: (2012)

A preclinical study demonstrating the efficacy of nilotinib in inhibiting the growth of pediatric high-grade glioma
por: Au, Karolyn, et al.
Publicado: (2015)

Effect of Podophyllotoxin Conjugated Stearic Acid Grafted Chitosan Oligosaccharide Micelle on Human Glioma Cells
por: Wang, Geng Huan, et al.
Publicado: (2020)

GliPR1 knockdown by RNA interference exerts anti‐glioma effects in vitro and in vivo
por: Scheuring, Urban J., et al.
Publicado: (2021)

Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting
por: Munthe, Sune, et al.
Publicado: (2016)

Effective combination of human bone marrow mesenchymal stem cells and minocycline in experimental autoimmune encephalomyelitis mice
por: Hou, Yun, et al.
Publicado: (2013)

Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas
por: Wu, Xing, et al.
Publicado: (2016)

Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy
por: Wang, Pei-Guo, et al.
Publicado: (2018)

Diffuse intrinsic pontine glioma cells are vulnerable to low intensity electric fields delivered by intratumoral modulation therapy
por: Deweyert, Andrew, et al.
Publicado: (2019)

Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma
por: Ghasimi, Soma, et al.
Publicado: (2016)

Shift of microRNA profile upon glioma cell migration using patient-derived spheroids and serum-free conditions
por: Munthe, Sune, et al.
Publicado: (2017)

SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway
por: Liu, Chuanjin, et al.
Publicado: (2017)

Dexamethasone and levetiracetam reduce hetero-cellular gap-junctional coupling between F98 glioma cells and glial cells in vitro
por: Ismail, Fatme Seval, et al.
Publicado: (2016)

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma
por: Zhang, Jiale, et al.
Publicado: (2018)

Correlation of the Beta-Trace Protein and Inflammatory Cytokines with Magnetic Resonance Imaging in Chronic Subdural Hematomas : A Prospective Study
por: Park, Ki-Su, et al.
Publicado: (2015)

Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics
por: Indira Chandran, Vineesh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t6rnc9hp4gpid06l9b014fbko0