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iRhom1 regulates proteasome activity via PAC1/2 under ER stress

Proteasome is a protein degradation complex that plays a major role in maintaining cellular homeostasis. Despite extensive efforts to identify protein substrates that are degraded through ubiquitination, the regulation of proteasome activity itself under diverse signals is poorly understood. In this...

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Detalles Bibliográficos
Autores principales: Lee, WonJae, Kim, YoungDoo, Park, Jisu, Shim, SangMi, Lee, Jieun, Hong, Se-hoon, Ahn, Hye-Hyun, Lee, Huikyong, Jung, Yong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479803/
https://www.ncbi.nlm.nih.gov/pubmed/26109405
http://dx.doi.org/10.1038/srep11559

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