Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production

Actinoplanes sp. SE50/110 produces the α-glucosidase inhibitor acarbose, which is used to treat type 2 diabetes mellitus. To obtain a comprehensive understanding of its cellular metabolism, a genome-scale metabolic model of strain SE50/110, iYLW1028, was reconstructed on the bases of the genome anno...

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Detalles Bibliográficos
Autores principales: Wang, Yali, Xu, Nan, Ye, Chao, Liu, Liming, Shi, Zhongping, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479805/
https://www.ncbi.nlm.nih.gov/pubmed/26161077
http://dx.doi.org/10.3389/fmicb.2015.00632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479805/
https://www.ncbi.nlm.nih.gov/pubmed/26161077
http://dx.doi.org/10.3389/fmicb.2015.00632

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