99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography

Total knee arthroplasty has witnessed a significant increase in recent years. Despite the advantages of this surgical procedure, it has some complications, the most serious of which is prosthetic infection. The discrimination of bacterial infections from sterile inflammatory processes is of great im...

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Autores principales: Kamaleshwaran, Koramadai Karuppusamy, Rajkumar, N, Mohanan, Vyshak, Kalarikal, Radhakrishnan, Shinto, Ajit Sugunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479918/
https://www.ncbi.nlm.nih.gov/pubmed/26170572
http://dx.doi.org/10.4103/0972-3919.158540
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author Kamaleshwaran, Koramadai Karuppusamy
Rajkumar, N
Mohanan, Vyshak
Kalarikal, Radhakrishnan
Shinto, Ajit Sugunan
author_facet Kamaleshwaran, Koramadai Karuppusamy
Rajkumar, N
Mohanan, Vyshak
Kalarikal, Radhakrishnan
Shinto, Ajit Sugunan
author_sort Kamaleshwaran, Koramadai Karuppusamy
collection PubMed
description Total knee arthroplasty has witnessed a significant increase in recent years. Despite the advantages of this surgical procedure, it has some complications, the most serious of which is prosthetic infection. The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of periprosthetic infection (PPI). Ubiquicidin (UBI) is a synthetic antimicrobial peptide fragment reported to be highly infection-specific. Tc99m-UBI has recently been reported to be a promising radiotracer for infection imaging. We report a case of left knee PPI diagnosed using 99mTc-UBI scintigraphy and compared with F-18 fluorodeoxy-glucose positron emission tomography.
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spelling pubmed-44799182015-07-13 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography Kamaleshwaran, Koramadai Karuppusamy Rajkumar, N Mohanan, Vyshak Kalarikal, Radhakrishnan Shinto, Ajit Sugunan Indian J Nucl Med Case Report Total knee arthroplasty has witnessed a significant increase in recent years. Despite the advantages of this surgical procedure, it has some complications, the most serious of which is prosthetic infection. The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of periprosthetic infection (PPI). Ubiquicidin (UBI) is a synthetic antimicrobial peptide fragment reported to be highly infection-specific. Tc99m-UBI has recently been reported to be a promising radiotracer for infection imaging. We report a case of left knee PPI diagnosed using 99mTc-UBI scintigraphy and compared with F-18 fluorodeoxy-glucose positron emission tomography. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4479918/ /pubmed/26170572 http://dx.doi.org/10.4103/0972-3919.158540 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamaleshwaran, Koramadai Karuppusamy
Rajkumar, N
Mohanan, Vyshak
Kalarikal, Radhakrishnan
Shinto, Ajit Sugunan
99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title_full 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title_fullStr 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title_full_unstemmed 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title_short 99m-Tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with F-18 fluorodeoxy-glucose positron emission tomography/computed tomography
title_sort 99m-tc-ubiquicidin scintigraphy in diagnosis of knee prosthesis infection and comparison with f-18 fluorodeoxy-glucose positron emission tomography/computed tomography
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479918/
https://www.ncbi.nlm.nih.gov/pubmed/26170572
http://dx.doi.org/10.4103/0972-3919.158540
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