The Disulfide Bond Cys255-Cys279 in the Immunoglobulin-Like Domain of Anthrax Toxin Receptor 2 Is Required for Membrane Insertion of Anthrax Protective Antigen Pore

Anthrax toxin receptors act as molecular clamps or switches that control anthrax toxin entry, pH-dependent pore formation, and translocation of enzymatic moieties across the endosomal membranes. We previously reported that reduction of the disulfide bonds in the immunoglobulin-like (Ig) domain of th...

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Detalles Bibliográficos
Autores principales: Jacquez, Pedro, Avila, Gustavo, Boone, Kyle, Altiyev, Agamyrat, Puschhof, Jens, Sauter, Roland, Arigi, Emma, Ruiz, Blanca, Peng, Xiuli, Almeida, Igor, Sherman, Michael, Xiao, Chuan, Sun, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479931/
https://www.ncbi.nlm.nih.gov/pubmed/26107617
http://dx.doi.org/10.1371/journal.pone.0130832

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