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An Alternative Phosphorylation Switch in Integrin β2 (CD18) Tail for Dok1 Binding
Integrins are involved in cell migration and adhesion. A large number of proteins interact with the cytoplasmic tails of integrins. Dok1 is a negative regulator of integrin activation and it binds to the phosphorylated membrane proximal NxxY motif in a number of integrin β tails. The β tail of the β...
Autores principales: | Gupta, Sebanti, Chit, Joel Chia-Yeong, Feng, Chen, Bhunia, Anirban, Tan, Suet-Mien, Bhattacharjya, Surajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479986/ https://www.ncbi.nlm.nih.gov/pubmed/26108885 http://dx.doi.org/10.1038/srep11630 |
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