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Nanopore sensing of individual transcription factors bound to DNA
Transcription factor (TF)-DNA interactions are the primary control point in regulation of gene expression. Characterization of these interactions is essential for understanding genetic regulation of biological systems and developing novel therapies to treat cellular malfunctions. Solid-state nanopor...
Autores principales: | Squires, Allison, Atas, Evrim, Meller, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479991/ https://www.ncbi.nlm.nih.gov/pubmed/26109509 http://dx.doi.org/10.1038/srep11643 |
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