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Exploring the role of drug-metabolising enzymes in antidepressant side effects

RATIONALE: Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly polymorphic nature of these enzymes has been linked to variability in antidepressant metabolism rates, leading to hope regarding the use of P450 genotyping to guide treatment. However, evidence that P45...

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Detalles Bibliográficos
Autores principales:	Hodgson, Karen, Tansey, Katherine E., Uher, Rudolf, Dernovšek, Mojca Zvezdana, Mors, Ole, Hauser, Joanna, Souery, Daniel, Maier, Wolfgang, Henigsberg, Neven, Rietschel, Marcella, Placentino, Anna, Craig, Ian W., Aitchison, Katherine J., Farmer, Anne E., Dobson, Richard J. B., McGuffin, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480333/ https://www.ncbi.nlm.nih.gov/pubmed/25761838 http://dx.doi.org/10.1007/s00213-015-3898-x

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