Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells

AMPK regulates many metabolic pathways including fatty acid and glucose metabolism, both of which are closely associated with insulin secretion in pancreatic β-cells. Insulin secretion is regulated by metabolic coupling factors such as ATP/ADP ratio and other metabolites generated by the metabolism...

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Detalles Bibliográficos
Autores principales: ElAzzouny, Mahmoud A., Evans, Charles R., Burant, Charles F, Kennedy, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480354/
https://www.ncbi.nlm.nih.gov/pubmed/26107620
http://dx.doi.org/10.1371/journal.pone.0129029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480354/
https://www.ncbi.nlm.nih.gov/pubmed/26107620
http://dx.doi.org/10.1371/journal.pone.0129029

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