Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinit...

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Autores principales: Ramos, Irene, Mansour, Mena, Wohlbold, Teddy J., Ermler, Megan E., Hirsh, Ariana, Runstadler, Jonathan A., Fernandez-Sesma, Ana, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480385/
https://www.ncbi.nlm.nih.gov/pubmed/26079843
http://dx.doi.org/10.3201/eid2107.141755
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author Ramos, Irene
Mansour, Mena
Wohlbold, Teddy J.
Ermler, Megan E.
Hirsh, Ariana
Runstadler, Jonathan A.
Fernandez-Sesma, Ana
Krammer, Florian
author_facet Ramos, Irene
Mansour, Mena
Wohlbold, Teddy J.
Ermler, Megan E.
Hirsh, Ariana
Runstadler, Jonathan A.
Fernandez-Sesma, Ana
Krammer, Florian
author_sort Ramos, Irene
collection PubMed
description Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.
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spelling pubmed-44803852015-07-01 Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus Ramos, Irene Mansour, Mena Wohlbold, Teddy J. Ermler, Megan E. Hirsh, Ariana Runstadler, Jonathan A. Fernandez-Sesma, Ana Krammer, Florian Emerg Infect Dis Dispatch Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors. Centers for Disease Control and Prevention 2015-07 /pmc/articles/PMC4480385/ /pubmed/26079843 http://dx.doi.org/10.3201/eid2107.141755 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ramos, Irene
Mansour, Mena
Wohlbold, Teddy J.
Ermler, Megan E.
Hirsh, Ariana
Runstadler, Jonathan A.
Fernandez-Sesma, Ana
Krammer, Florian
Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title_full Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title_fullStr Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title_full_unstemmed Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title_short Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
title_sort hemagglutinin receptor binding of a human isolate of influenza a(h10n8) virus
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480385/
https://www.ncbi.nlm.nih.gov/pubmed/26079843
http://dx.doi.org/10.3201/eid2107.141755
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