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MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014

To assess the temporal dynamics of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in dromedary camels, specimens were collected at 1–2 month intervals from 2 independent groups of animals during April 2013–May 2014 in Al-Ahsa Province, Saudi Arabia, and tested for MERS-CoV RNA by...

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Autores principales: Khalafalla, Abdelmalik I., Lu, Xiaoyan, Al-Mubarak, Abdullah I.A., Dalab, Abdul Hafeed S., Al-Busadah, Khalid A.S., Erdman, Dean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480395/
https://www.ncbi.nlm.nih.gov/pubmed/26079346
http://dx.doi.org/10.3201/eid2107.150070
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author Khalafalla, Abdelmalik I.
Lu, Xiaoyan
Al-Mubarak, Abdullah I.A.
Dalab, Abdul Hafeed S.
Al-Busadah, Khalid A.S.
Erdman, Dean D.
author_facet Khalafalla, Abdelmalik I.
Lu, Xiaoyan
Al-Mubarak, Abdullah I.A.
Dalab, Abdul Hafeed S.
Al-Busadah, Khalid A.S.
Erdman, Dean D.
author_sort Khalafalla, Abdelmalik I.
collection PubMed
description To assess the temporal dynamics of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in dromedary camels, specimens were collected at 1–2 month intervals from 2 independent groups of animals during April 2013–May 2014 in Al-Ahsa Province, Saudi Arabia, and tested for MERS-CoV RNA by reverse transcription PCR. Of 96 live camels, 28 (29.2%) nasal swab samples were positive; of 91 camel carcasses, 56 (61.5%) lung tissue samples were positive. Positive samples were more commonly found among young animals (<4 years of age) than adults (>4 years of age). The proportions of positive samples varied by month for both groups; detection peaked during November 2013 and January 2014 and declined in March and May 2014. These findings further our understanding of MERS-CoV infection in dromedary camels and may help inform intervention strategies to reduce zoonotic infections.
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spelling pubmed-44803952015-07-01 MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014 Khalafalla, Abdelmalik I. Lu, Xiaoyan Al-Mubarak, Abdullah I.A. Dalab, Abdul Hafeed S. Al-Busadah, Khalid A.S. Erdman, Dean D. Emerg Infect Dis Research To assess the temporal dynamics of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in dromedary camels, specimens were collected at 1–2 month intervals from 2 independent groups of animals during April 2013–May 2014 in Al-Ahsa Province, Saudi Arabia, and tested for MERS-CoV RNA by reverse transcription PCR. Of 96 live camels, 28 (29.2%) nasal swab samples were positive; of 91 camel carcasses, 56 (61.5%) lung tissue samples were positive. Positive samples were more commonly found among young animals (<4 years of age) than adults (>4 years of age). The proportions of positive samples varied by month for both groups; detection peaked during November 2013 and January 2014 and declined in March and May 2014. These findings further our understanding of MERS-CoV infection in dromedary camels and may help inform intervention strategies to reduce zoonotic infections. Centers for Disease Control and Prevention 2015-07 /pmc/articles/PMC4480395/ /pubmed/26079346 http://dx.doi.org/10.3201/eid2107.150070 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Khalafalla, Abdelmalik I.
Lu, Xiaoyan
Al-Mubarak, Abdullah I.A.
Dalab, Abdul Hafeed S.
Al-Busadah, Khalid A.S.
Erdman, Dean D.
MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title_full MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title_fullStr MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title_full_unstemmed MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title_short MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014
title_sort mers-cov in upper respiratory tract and lungs of dromedary camels, saudi arabia, 2013–2014
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480395/
https://www.ncbi.nlm.nih.gov/pubmed/26079346
http://dx.doi.org/10.3201/eid2107.150070
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