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Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case–control study
BACKGROUND: The p16-Leiden founder mutation in the CDKN2A gene is the most common cause of Familial Atypical Multiple Mole Melanoma (FAMMM) syndrome in the Netherlands. Individuals with this mutation are at increased risk for developing melanoma of the skin, as well as pancreatic cancer. However, th...
Autores principales: | Potjer, Thomas P, van der Stoep, Nienke, Houwing-Duistermaat, Jeanine J, Konings, Ingrid C A W, Aalfs, Cora M, van den Akker, Peter C, Ausems, Margreet G, Dommering, Charlotte J, van der Kolk, Lizet E, Maiburg, Merel C, Spruijt, Liesbeth, Wagner, Anja, Vasen, Hans F A, Hes, Frederik J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480449/ https://www.ncbi.nlm.nih.gov/pubmed/26111702 http://dx.doi.org/10.1186/s13104-015-1235-4 |
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