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Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes

BACKGROUND: Increasing evidences link T helper 17 (Th17) cells with multiple sclerosis (MS). In this context, interleukin-22 (IL-22), a Th17-linked cytokine, has been implicated in blood brain barrier breakdown and lymphocyte infiltration. Furthermore, polymorphism between MS patients and controls h...

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Detalles Bibliográficos
Autores principales:	Perriard, Guillaume, Mathias, Amandine, Enz, Lukas, Canales, Mathieu, Schluep, Myriam, Gentner, Melanie, Schaeren-Wiemers, Nicole, Du Pasquier, Renaud A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480507/ https://www.ncbi.nlm.nih.gov/pubmed/26077779 http://dx.doi.org/10.1186/s12974-015-0335-3

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