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The therapeutic effect of methotrexate-conjugated Pluronic-based polymeric micelles on the folate receptor-rich tumors treatment
The therapeutic effect of methotrexate (MTX)-conjugated Pluronic-based polymeric mixed micelles (F127/P105-MTX) on the folate receptor-overexpressing tumors treatment was investigated in this study. Due to its high structural similarity to folic acid and the high expression of folate receptor in mos...
Autores principales: | Chen, Yanzuo, Zhang, Wei, Huang, YuKun, Gao, Feng, Sha, Xianyi, Lou, Kaiyan, Fang, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480589/ https://www.ncbi.nlm.nih.gov/pubmed/26150715 http://dx.doi.org/10.2147/IJN.S79045 |
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