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BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner

BRCA1 plays a key role in the regulation of p53-dependent target gene transcription activation. Meanwhile, the p53 inducible gene 3 (PIG3) is a downstream target of p53 and is involved in p53-initiated apoptosis. However, little is known about whether BRCA1 can regulate PIG3-mediated apoptosis. Usin...

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Detalles Bibliográficos
Autores principales: Zhang, Wenwen, Luo, Jiayan, Chen, Fengxia, Yang, Fang, Song, Wei, Zhu, Aiyu, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480703/
https://www.ncbi.nlm.nih.gov/pubmed/25797244